diff --git a/crates/oxc/src/compiler.rs b/crates/oxc/src/compiler.rs
index 8c95baf04..fe9efb716 100644
--- a/crates/oxc/src/compiler.rs
+++ b/crates/oxc/src/compiler.rs
@@ -152,6 +152,7 @@ pub trait CompilerInterface {
             return;
         }
 
+        let stats = semantic_return.semantic.stats();
         let (mut symbols, mut scopes) = semantic_return.semantic.into_symbol_table_and_scope_tree();
 
         /* Transform */
@@ -169,20 +170,34 @@ pub trait CompilerInterface {
                 return;
             }
 
-            symbols = transformer_return.symbols;
-            scopes = transformer_return.scopes;
+            (symbols, scopes) = (transformer_return.symbols, transformer_return.scopes);
         }
 
-        if let Some(config) = self.inject_options() {
-            let ret =
-                InjectGlobalVariables::new(&allocator, config).build(symbols, scopes, &mut program);
+        let inject_options = self.inject_options();
+        let define_options = self.define_options();
+
+        // Symbols and scopes are out of sync.
+        if inject_options.is_some() || define_options.is_some() {
+            (symbols, scopes) = SemanticBuilder::new()
+                .with_stats(stats)
+                .build(&program)
+                .semantic
+                .into_symbol_table_and_scope_tree();
+        }
+
+        if let Some(options) = inject_options {
+            let ret = InjectGlobalVariables::new(&allocator, options).build(
+                symbols,
+                scopes,
+                &mut program,
+            );
             symbols = ret.symbols;
             scopes = ret.scopes;
         }
 
-        if let Some(config) = self.define_options() {
+        if let Some(options) = define_options {
             let ret =
-                ReplaceGlobalDefines::new(&allocator, config).build(symbols, scopes, &mut program);
+                ReplaceGlobalDefines::new(&allocator, options).build(symbols, scopes, &mut program);
             Compressor::new(&allocator, CompressOptions::dead_code_elimination())
                 .build_with_symbols_and_scopes(ret.symbols, ret.scopes, &mut program);
             // symbols = ret.symbols;
diff --git a/napi/transform/index.d.ts b/napi/transform/index.d.ts
index e18b5bd3b..4c76416ab 100644
--- a/napi/transform/index.d.ts
+++ b/napi/transform/index.d.ts
@@ -203,8 +203,6 @@ export interface TransformOptions {
   typescript?: TypeScriptOptions
   /** Configure how TSX and JSX are transformed. */
   jsx?: JsxOptions
-  /** Enable ES2015 transformations. */
-  es2015?: Es2015Options
   /** Define Plugin */
   define?: Record<string, string>
   /** Inject Plugin */
diff --git a/napi/transform/test/transform.test.mjs b/napi/transform/test/transform.test.mjs
index 7b5e71586..4230849e3 100644
--- a/napi/transform/test/transform.test.mjs
+++ b/napi/transform/test/transform.test.mjs
@@ -63,9 +63,8 @@ $RefreshReg$(_c, "App");
 });
 
 describe('define plugin', () => {
-  const code = 'if (process.env.NODE_ENV === "production") { foo; }';
-
   it('matches output', () => {
+    const code = 'if (process.env.NODE_ENV === "production") { foo; }';
     const ret = oxc.transform('test.tsx', code, {
       define: {
         'process.env.NODE_ENV': '"development"',
@@ -73,6 +72,16 @@ describe('define plugin', () => {
     });
     assert.equal(ret.code, '');
   });
+
+  it('handles typescript declare global', () => {
+    const code = 'declare let __TEST_DEFINE__: string; console.log({ __TEST_DEFINE__ });';
+    const ret = oxc.transform('test.ts', code, {
+      define: {
+        '__TEST_DEFINE__': '"replaced"',
+      },
+    });
+    assert.equal(ret.code, 'console.log({ __TEST_DEFINE__: "replaced" });\n');
+  });
 });
 
 describe('inject plugin', () => {